產(chǎn)品名稱:anti-ZBP1, mAb (Zippy-1)

別名:Z-DNA-binding Protein 1; Tumor Stroma and Activated Macrophage Protein DLM-1; DNA-dependent Activator of IFN-regulatory Factors; DAI

產(chǎn)品描述:ZBP1 is an interferon inducible protein that binds to cytoplasmic DNA and plays a role in host defense against tumors and pathogens. ZBP1 is highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow and spleen. ZBP1 is an innate immune sensor of Influenza A virus (IAV). ZBP1 regulates NLRP3 (nucleotide and oligomerization domain, leucine-rich repeat-containing protein family, pyrin domain containing 3) inflammasome activation as well as induction of different types of cell death (apoptosis, necroptosis and pyroptosis) during IAV infection.

反應(yīng)種屬:Human, Mouse

實驗應(yīng)用:ICC, IP, WB

同種型:Mouse IgG2a

免疫原:Recombinant mouse ZBP1 (aa 1-411).

克隆性:Monoclonal

克隆號:Zippy-1

產(chǎn)品濃度:1mg/ml

保存溫度:-20°C

運輸溫度:BI

產(chǎn)品形式:liquid

存儲溶液:Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.

有效期:Stable for at least 1 year after receipt when stored at -20°C.

產(chǎn)地:瑞士

生產(chǎn)商:AdipoGen Life Sciences

樣本類型:Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.

純度:1mg/ml

來源:Purified from concentrated hybridoma tissue culture supernatant.

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